Clinical Operations Executive & Medical Director of Sites
- Samantha Wein
- Apr 6
- 2 min read
Updated: Apr 24
An ECFMG-certified physician and U.S. Citizen with over a decade of clinical research leadership, specializing in the operational turnaround and management of large-scale Phase II–IV trial sites. This leader has successfully overseen multi-disciplinary teams of up to 30 reports and managed high-complexity portfolios across neurology, vaccines, and metabolic disease.
Core Competencies
Site Network Leadership: Expert in managing multi-site operations, site feasibility, and rapid study start-up for "Big Pharma" and CRO sponsors.
Medical & Scientific Oversight: Deep clinical roots with experience in EDSS assessment, stroke biomarkers, and complex therapeutic areas including Immunology and Rare Disease.
Financial & P&L Management: Proven track record in forecasting operating budgets, optimizing site revenue, and driving patient recruitment diversity.
Compliance & SOP Architecture: Developed 25+ customized SOPs to ensure GCP compliance and audit readiness for FDA/regulatory inspections.
Key Career Milestones
Operational Excellence in Vaccines: Served as Director of Operations for a premier clinical site, managing a 30-person team and gaining national recognition for high-enrollment and high-quality execution of Phase II+ vaccine trials.
M&A & Site Integration: Acted as Interim Site Director for a major private-equity-backed research network, stabilizing site financials and exceeding monthly KPI targets during leadership transitions.
Therapeutic Depth (Neurology & Stroke): Established a comprehensive research site within a major regional hospital, leading clinical trials focused on stroke biomarkers and autonomic lab diagnostics.
Global Remote Operations: Founded and scaled a remote clinical support organization that provides medical scribing, regulatory support, and patient recruitment services to U.S.-based research sites.
Scientific Contribution: Co-authored peer-reviewed research in high-impact journals (e.g., Journal of Asthma, Stroke and Vascular Neurology) and led NIH R01 grant application processes for clinical trials.
"Why Now"
Seeking a Senior Director of Clinical Operations, VP of Site Operations, or Regional Head role within a Sponsor, CRO, or Site Management Organization (SMO). They are an ideal fit for organizations looking to scale their site footprint, improve enrollment metrics, or bring medical-grade rigor to site-level operations.
Consultant Note: Unlike many site managers who come from a purely administrative background, this candidate’s MD training allows them to speak the language of Principal Investigators and Sponsors fluently. They are uniquely qualified to bridge the gap between protocol design and real-world site execution.
Interested in this candidate? To request a resume or schedule an interview, please book a consultation with our team or contact us directly using the links below.
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