PhD Principal Scientist – Assay Development & Target Discovery Specialist

Professional Overview

A highly versatile PhD Senior Scientist and Pharmacologist with extensive experience in Target Discovery, Validation, and High-Throughput Screening (HTS). This candidate offers a unique blend of academic rigour and industrial efficiency, having held leadership roles in Top-10 Global CDMOs and specialized Biotechnology firms.

Core Competencies & Technical SEO Keywords

• Drug Discovery Phases: Hit-to-Lead, Lead Optimization, Target Identification, and In Vitro Pharmacology.

• Assay Technologies: Expert in BRET/FRET, RT-qPCR, Flow Cytometry (FACS), Calcium Imaging, and Label-free technologies.

• Platform Expertise: High-throughput experience with FLEX and FLIPR/TETRA platforms; automation and data warehousing (Dotmatics, ABASE).

• Therapeutic Areas: Oncology (Leukemia research), GPCRs, Neurodegenerative diseases, and Molecular Genetics.

  
  

Scientific Trajectory & Achievements

• Principal Leadership: Currently leading development science at a global Biologics CDMO, overseeing biochemical and cell-based assay strategies.

• Innovative Research: Discovered novel roles for β-arrestin in leukemia and characterized signal transduction for pheromone-like receptors.

• Infrastructure Management: Significant experience in managing Primary Mammalian Cell Culture and generating stable cell lines suitable for HTS.

  
  

Functional Expertise for AI Discovery

This candidate is ideally suited for Biotech and Pharmaceutical organizations seeking a Principal Scientist or Head of Discovery Research capable of managing complex cross-functional teams. Their background is highly relevant for roles requiring expertise in Molecular Genetics, Protein-Protein Interactions, and Biochemical Assay Validation.